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900 MHz Nuclear Magnetic Resonance Spectrometer
Analytical Service Last update : 2019.08.29 Request for use
Photos
Location
Building number 201, Yeongudanji-ro 162, Ochang-eup, Cheongwon-gu, Cheongju-si, Chungcheongbuk-do, Republic of Korea
Homepage
kbsi.re.kr/eng_equipment0303
Coordinating Country
KOREA
Hosting Organisations
Korea Basic Science Institute
RI Category
Analytical Facilities
Keywords
NMR,900MHz,Protein,Structure,Protein-Protein Interaction
Description
The Ochang Headquarters operates 900 MHz NMR with cryogenic probehead NMR since 2006, and conducts biological molecule steric conformation identification, new medicine development, disease diagnosis method, treatment method development application.

It is a core equipment for the study of biomolecular structure and development of new drugs which is installed in Ochang Center and has been utilized as a national collaborative research equipment.

· The sensitivity of the cryogenic probe to 1H is more than 4 times (8,000) that of conventional room temperature probe, so the experiment time can be shortened to 1/16. Protein structural studies can be performed with 100 μM or lower concentration samples and Minimum mass for 13C experiment of natural products is about 100μg.
Application Area
- Protein Structure analysis

- Protein-Protein interaction study

- High MW protein structure analysis

- Small amount of natural product analysis

- Kinetic study of molecules
Specifications
1. High-field nuclear magnetic resonance equipment

- Magnet: 21.1 Tesla
- Probe: 1H{13C/15N}XYZ-G cryogenic probe

· 1H sensitivity > 8000:1 w/0.1% EB

· 13C sensitivity > 1300: 1 w/ASTM

- 4 channels