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Biobank Graz (BBG)
Date of Last update : 2019.02.28 Rivision Request
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Hosting Legal Entity
Medical University of Graz
Type Of RI
Single-sited
Location
Neue Stiftingtalstra? 2/B/2, Medical University of Graz - ZWT, Graz, PO: 8010 (Austria), Austria(47.079557, 15.467436)
Coordinating Country
Austria
Life Cycle Status
Operational since 2007
Mission and objective
Biobank Graz acts as a crossroad between different areas of diagnostic and research by providing high quality biological material and data. The collection currently contains several millions human samples representing both specific cohorts as well as a non-selected patient group characteristic of Central Europe. The services comprise managerial support (e.g. project implementation) as well as technical support (e.g. preparation of derivatives) to academic and industrial research. Biobank Graz is also an active member of BBMRI-ERIC, ESBB and ISBER, which represent the three most important societies in biobanking.
RI Keywords
Biobanks,FFPE,Tissue paraffin preserved,Tissue cryo preserved,Serum,Plasma,Whole blood,Buffy coat,Urine,Liquor,Seminal plasma,Follicle liquid,Cumulus cells,Cord blood serum,Cord blood plasma,ISO 9001
RI Category
Collections of Biological Resources (e.g. Microorganisms, Biobanks and Seed Banks)
Scientific Domain
Biological and Medical Sciences
Access WebPage
https://biobank.medunigraz.at/

Equipment

- Hamilton MICROLAB STAR

The custom-made pipetting robot recognizes 1D- and 2D-barcodes on tubes via barcode reader to identify the type of sample, volume containing in the tube and the demand of aliquotation. The automatic capping and decapping of the tubes, included freezing station for medium-term storage at -15°C as well as connection to the laboratory information system is the convenience of this device.

- Hamilton BIOS Store

The Biobank Graz new storage system for liquid samples is a fully automated -80°C storage system with 9 storage bays. Tubes can be stored and retrieved automatically via the single picking module in the isolated -80°C input/output buffer zone. Mechanical cascade-refrigeration circuitskeep the temperature in the storage area at -80°C. Active air dehumidification in the processing compartment and a full temperature monitoring system ensure high quality storage for all Biobank samples.

- YLOG - storage system

This semi-automated system enables efficient storage of FFPE-blocks and slides. The 2-D encoded blocks and slides as well as their storage position are scanned manually while this information is saved in the central Biobank database. All samples are stored in especially designed boxes that are transported via automated intelligent vehicles to their storage position. Output and restoring of samples is handled easily via computer.

- Hamilton MICROLAB STARlet

This pipetting robot enables the Biobank Graz to automatically pipette liquid samples from smaller studies with varying aliquots and handling demands. Therefore there is no freezing unit included in this device, so that the aliquoted tubes can be transported to the storage straight away. This pipetting robot also comprises of a barcode reader, an integrated camera and the link to our database.

- LiCONiC KiWi Store

Most of the liquidsamples of Biobank Graz arestored at the fully automated LiCONiC KiWi Store. This storage system comprises of a -20°.C handling zone with a single tube picker and a-80°.C zone where the samples are stored chaotically. 1-D and 2-D bar codes are scanned via this deviceand associated data is stored in the central Biobank database.

- Askion C-line - hermetic storage 200/201

In addition to 9 conventional tanks for cryopreservation, the Biobank Graz stores tissue samples in the ASKION C-line hermetic storage HS200. It consists of the working room with a temperature of -80°.C to -110°.C and the storing container with a temperature of -150°.C (gasphase of liquid nitrogen). The sample handling works through the operatorport via a pair of heated gloves. The storage position of the samples is automatically allocated within 6 storage racks, rotatable on a carousel. Continuous cold chain, a rapid storing process and recording of all relevant sample data are the advantages of this device.

Service

- Prospective sample collection

Biobank Graz provides powerful logistics and infrastructure enabling prospective collection of samples and data designed according to the needs specified by customers. One of the competences is also the planning and realisation of prospective study cohorts.Professional support in all biobank-related research questions is offered by the project management team, especially concerning biobank samples as well as customer and researcher requests.

- Integration of pre-existing collections into Biobank Graz

Since Biobank Graz offers powerful logistics as well as storage and data handling with well-trained Biobanking staff, an integration of pre-existing collections is a possibilty to ensure save storage.

- Provision of biological samples and associated data

Biobank Graz houses a large collection of clinical samples, comprising millions of well organized tissue and liquid samples and associated data. It offers professional support in all research questions concerning biobank samples and handles customer and researcher requests.

- Contact to and networking with other biobanks

Biobank Graz is an active and leading player in (inter-) national projects and activities aimed at improving interactions between and cooperation amongst biobanks. Biobank Graz was involved in several projects under the 7th Framework programme as well as the HORIZON 2020 programme of the EU.Moeover, Biobank Graz is one of the members of BBMRI.at, the national node of BBMRI-ERIC, which is aiming at improving biobanking collaboration on a European level. Since BBMRI.at and BBMRI-ERIC both are located in the same building as Biobank Graz, a good connection on a daily basis is given. Also, Biobank Graz is member of the European, Middle Eastern and African Society for Biopreservation and Biobanking (ESBB) as well as the International Society for Biological and Environmental Repositories (ISBER).

- Consulting and Training

Continued education and well-trained personnel are a prerequisite for biobanks. Since Biobank Graz staff has comprehensive experience (concerning legal, ethical, technical and organisational aspects in biobanking), training and consulting for biobanking personnel is one of our services. Also the support at the installation of new biobanks is a field of activity.

- Analysis of samples

For further analysis of biobanking samples Biobank Graz collaborates with the following Core Facilities of the Medical University of Graz: Flow Cytometry, Mass Spectometry (Lipidomics and Proteomics), Microscopy, Molecular Biology including NGS and Ultrastructure Analysis.