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900 MHz Nuclear Magnetic Resonance Spectrometer
Facility name
Hosting Legal Entity
Korea Basic Science Institute
Contact
eunhee5063@gmail.com  Send E-Mail

haknam81@gmail.com  Send E-Mail
RI Category
Analytical Facilities
RI Keywords
NMR,900MHz,Protein,Structure,Protein-Protein Interaction
TRL
  1. Basic Technology
    Research
    1단계 2단계
  2. Research to Prove
    Feasibility
    3단계 4단계
  3. Technology
    Demonstration
    5단계 6단계
  4. System/Subsystem
    Development
    7단계 8단계
  5. System Test
    Launch &
    Operaions
    9단계
Description
3 DAY + 1PREP

The Ochang Headquarters operates 900 MHz NMR with cryogenic probehead NMR since 2006, and conducts biological molecule steric conformation identification, new medicine development, disease diagnosis method, treatment method development application. It is a core equipment for the study of biomolecular structure and development of new drugs which is installed in Ochang Center and has been utilized as a national collaborative research equipment. · The sensitivity of the cryogenic probe to 1H is more than 4 times (8,000) that of conventional room temperature probe, so the experiment time can be shortened to 1/16. Protein structural studies can be performed with 100 μM or lower concentration samples and Minimum mass for 13C experiment of natural products is about 100μg.
Application Area
- Protein Structure analysis - Protein-Protein interaction study - High MW protein structure analysis - Small amount of natural product analysis - Kinetic study of molecules
Specifications
1. High-field nuclear magnetic resonance equipment - Magnet: 21.1 Tesla
- Probe: 1H{13C/15N}XYZ-G cryogenic probe · 1H sensitivity > 8000:1 w/0.1% EB · 13C sensitivity > 1300: 1 w/ASTM - 4 channels

Equipment Component

Equipment Component

Provide name and model item

Name Model
400 MHz NMR spectrometer AVANCE III 400 | Bruker
800MHz NMR Cryogenic Probehead Cryoprobe | Bruker
900MHz NMR(Nuclear Magnetic Resonance) AVANCE II 900 | Bruker
700MHz NMR spectrometer AVANCE III HD | Bruker
800MHz NMR(Nuclear Magnetic Resonance) AVANCE 800 | Bruker
900 MHz NMR spectrometer console and cryogenic probehead AVANCE NEO 900 | Bruker

location

Building number 201, Yeongudanji-ro 162, Ochang-eup, Cheongwon-gu, Cheongju-si, Chungcheongbuk-do, Republic of Korea

Photos

  • 400_nmr.jpg
  • photo1 (1).jpg
  • NFEC-2007-06-056254.JPG
  • 사진.JPG
  • NFEC-2007-06-056253.jpg
  • 6058720190121145743_21.jpg